The Colorado General Assembly has recently enacted Senate Bill 23-290, codified at CRS 44- 50-101, creating a regulatory structure for the operation of licensed facilities for the supervised use of natural medicines by individuals age 21 and over. The Act creates a state agency responsible for licensing and registration of facilities and related businesses that provide for the use, cultivation, manufacture, and testing of these substances. Further, the state licensing authority will not issue licenses for any building which is within 1000 feet of a childcare center, preschool, elementary, middle, junior high school, or residential childcare facility. While the state statute does not require local governments to enact any local regulations of natural medicine businesses, the City has the authority to do so, and several municipalities across the state have chosen to enact various forms of regulation, while other communities have decided not to. Under the Act, the City may regulate the time, place and manner of the operation of healing centers licensed by the state but may not prohibit the uses entirely. The City may not prohibit licensed health care facilities or individuals from providing natural medicine services within the City, nor may it prohibit the transportation of natural medicine on public roads within the City. Finally, according to the Act, the City may not impose regulations that are “unreasonable or in conflict with the [Act].”